GCH1 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P30793 |
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Other Accession | NP_000152.1, NP_001019195.1, NP_001019242.1, NP_001019241.1 |
Clone Names | 90415066 |
Gene ID | 2643 |
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Other Names | GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I, GCH1, DYT5, GCH |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GCH1 |
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Synonyms | DYT5, GCH |
Function | Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown. |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level). |
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