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PEX7 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession O00628
Other Accession NP_000279.1
Clone Names 90909093
Additional Information
Gene ID 5191
Other Names Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7, PEX7, PTS2R
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PEX7 {ECO:0000303|PubMed:9090383, ECO:0000312|HGNC:HGNC:8860}
Function Receptor required for the peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal (PubMed:9090381, PubMed:11931631, PubMed:22057399, PubMed:25538232). Specifically binds to cargo proteins containing a PTS2 peroxisomal targeting signal in the cytosol (PubMed:11931631, PubMed:22057399, PubMed:25538232). Cargo protein-binding triggers interaction with PEX5 and formation of a ternary complex composed of PEX5 and PEX7 along with PTS2-containing cargo proteins, which is tranlocated into peroxisomes by passing through the PEX13-PEX14 docking complex (PubMed:11546814, PubMed:25538232).
Cellular Location Cytoplasm, cytosol. Peroxisome matrix. Note=Translocated into the peroxisome matrix together with PTS2-containing cargo proteins and PEX5
Tissue Location Ubiquitous (PubMed:9090381). Highest expression in pancreas, skeletal muscle and heart (PubMed:9090381)
Research Areas
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$ 277.78
Cat# BP5899a
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