|Other Accession||NP_038464.1, NP_995314.1|
|Other Names||Nck-associated protein 1, NAP 1, Membrane-associated protein HEM-2, p125Nap1, NCKAP1, HEM2, KIAA0587, NAP1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||HEM2, KIAA0587, NAP1|
|Function||Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1.|
|Cellular Location||Cell membrane; Single-pass membrane protein; Cytoplasmic side Cell projection, lamellipodium membrane; Single-pass membrane protein; Cytoplasmic side Note=At the interface between the lamellipodial actin meshwork and the membrane.|
|Tissue Location||Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle|
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