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ZFAN5 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O76080
Other Accession NP_001095891.1, NP_005998.1, NP_001095890.1
Clone Names 91119114
Peptide ID 91119114
Additional Information
Gene ID 7763
Other Names AN1-type zinc finger protein 5, Zinc finger A20 domain-containing protein 2, Zinc finger protein 216, ZFAND5, ZA20D2, ZNF216
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ZA20D2, ZNF216
Function Involved in protein degradation via the ubiquitin- proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4- induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in skeletal muscle. Expressed in fetal cochlea. Also expressed in infant brain, fetal heart, pancreatic islet, melanocyte, pineal gland, placenta, corneal stroma, and parathyroid tumor. Weakly expressed or undetectable in adult brain, heart, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes Expressed in rhabdomyosarcoma RD cells (at protein level)
Research Areas
Citations (0)

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$ 80.00
Cat# BP5929b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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