|Other Accession||NP_065790.2, NP_004739.3|
|Other Names||Cell cycle progression protein 1, Cell cycle progression restoration protein 8, CCPG1, CCP8, CPR8, KIAA1254|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CCP8, CPR8, KIAA1254|
|Function||Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42 (By similarity). May be involved in cell cycle regulation.|
|Cellular Location||Cytoplasmic granule membrane; Single-pass type II membrane protein|
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