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SARS virus PUP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6VA99
Other Accession NP_828852
Clone Names 3042701
Additional Information
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6001a was selected from the N-term region of human SARS virus PUP1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Q6VA99
Research Areas
Citations (0)

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Background

The SARS-CoV genome contains five major open reading frames (ORFs) that encode the replicase polyprotein (R), the spike (S), envelope (E), and membrane (M) glycoproteins; and the nucleocapsid protein (N). Other proteins not falling into these categories have been termed PUPs (putative uncharacterized proteins) for their unknown structural or functional features and dissimilarity to those known sequences. However, it has been found that some of the PUPs matched the entries in the NCBI database. PUP1 is equivalent to ORF3 in Isolate Tor2. It receives 11 hits in GenBank through BLAST, two of which are putative transmembrane proteins. One is from Ralstonia solanacearum, cytochrome b-561, with 97 amino acids of PUP1 aligned, and the other is from Sinorhizobium meliloti, with 94 amino acids aligned. Sequence identities are 28% and 25%, respectively. Three putative transmembrane domains are located within PUP1.

References

He, R., et al., Biochem. Biophys. Res. Commun. 316(2):476-483 (2004).Snijder, E.J., et al., J. Mol. Biol. 331(5):991-1004 (2003).Marra, M.A., et al., Science 300(5624):1399-1404 (2003).

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$ 80.00
Cat# BP6001a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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