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ABCB6 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NP58
Clone Names 2080205
Peptide ID 2080205
Additional Information
Gene ID 10058
Other Names ATP-binding cassette sub-family B member 6, mitochondrial, Mitochondrial ABC transporter 3, Mt-ABC transporter 3, P-glycoprotein-related protein, Ubiquitously-expressed mammalian ABC half transporter, ABCB6, MTABC3, PRP, UMAT
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6113a was selected from the C-term region of human ABCB6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCB6
Synonyms MTABC3, PRP, UMAT
Function Binds heme and porphyrins and functions in their ATP- dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
Cellular Location Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Endosome. Note=localized to the endosome- like compartement and dendrite tips
Tissue Location Widely expressed. High expression is detected in the retinal epithelium.
Research Areas
Citations (0)

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The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.


Mitsuhashi, N., et al., J. Biol. Chem. 275(23):17536-17540 (2000).Furuya, K.N., et al., Cancer Res. 57(17):3708-3716 (1997).Allikmets, R., et al., Hum. Mol. Genet. 5(10):1649-1655 (1996).

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$ 80.00
Cat# BP6113a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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