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ABCB7 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75027
Other Accession NP_004290
Clone Names 2080206
Peptide ID 2080206
Additional Information
Gene ID 22
Other Names ATP-binding cassette sub-family B member 7, mitochondrial, ATP-binding cassette transporter 7, ABC transporter 7 protein, ABCB7, ABC7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6114a was selected from the C-term region of human ABCB7 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ABCB7
Synonyms ABC7
Function Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein {ECO:0000255|PROSITE- ProRule:PRU00441}
Research Areas
Citations (0)

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The membrane-associated protein ABCB7 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been implicated in X-linked sideroblastic anemia with ataxia.


Allikmets, R., et al., Hum. Mol. Genet. 8(5):743-749 (1999).Csere, P., et al., FEBS Lett. 441(2):266-270 (1998).Mao, M., et al., Proc. Natl. Acad. Sci. U.S.A. 95(14):8175-8180 (1998).Shimada, Y., et al., J. Hum. Genet. 43(2):115-122 (1998).Savary, S., et al., Genomics 41(2):275-278 (1997).

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$ 80.00
Cat# BP6114a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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