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EDG6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O95977
Other Accession NP_003766
Clone Names 2080605
Additional Information
Gene ID 8698
Other Names Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6, S1PR4, EDG6
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6142a was selected from the N-term region of human EDG6 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name S1PR4
Synonyms EDG6
Function Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung
Research Areas
Citations (0)

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EDG6 is a member of the G protein-coupled receptors, as well as the EDG family of proteins. It participates in endothelial differentiation, and may regulate lymphocyte cell signaling. It is a member of the lysophospholipid/lysosphingolipid receptor family.


Contos, J.J., et al., FEBS Lett. 531(1):99-102 (2002).Yamazaki, Y., et al., Biochem. Biophys. Res. Commun. 268(2):583-589 (2000).Graler, M.H., et al., Genomics 53(2):164-169 (1998).

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$ 80.00
Cat# BP6142a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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