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EDG7 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UBY5
Clone Names 2092011
Additional Information
Gene ID 23566
Other Names Lysophosphatidic acid receptor 3, LPA receptor 3, LPA-3, Lysophosphatidic acid receptor Edg-7, LPAR3, EDG7, LPA3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6143a was selected from the C-term region of human EDG7 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LPAR3
Synonyms EDG7, LPA3
Function Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes
Research Areas
Citations (0)

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EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.


Fujita, T., et al., Cancer Lett. 192(2):161-169 (2003).Im, D.S., et al., Mol. Pharmacol. 57(4):753-759 (2000).Fitzgerald, L.R., et al., Biochem. Biophys. Res. Commun. 273(3):805-810 (2000).Bandoh, K., et al., J. Biol. Chem. 274(39):27776-27785 (1999).Hama, K., et al., FEBS Lett. 523 (1-3), 187-192 (2002).

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$ 80.00
Cat# BP6143a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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