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MAGEA11 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P43364
Other Accession NP_005357
Clone Names 2091107
Peptide ID 2091107
Additional Information
Gene ID 4110
Other Names Melanoma-associated antigen 11, Cancer/testis antigen 111, CT111, MAGE-11 antigen, MAGEA11, MAGE11
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6161a was selected from the N-term region of human MAGEA11 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAGEA11
Synonyms MAGE11
Function Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma. Expressed in testis, ovary, prostate, cancerous prostate, breast and adrenal tissue
Research Areas
Citations (0)

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MAGEA11 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.


Rogner, U.C., et al., Genomics 29(3):725-731 (1995).De Plaen, E., et al., Immunogenetics 40(5):360-369 (1994).

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$ 80.00
Cat# BP6161a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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