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MMP19 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q99542
Other Accession NP_002420
Clone Names 2090502
Peptide ID 2090502
Additional Information
Gene ID 4327
Other Names Matrix metalloproteinase-19, MMP-19, 3424-, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-18, MMP19, MMP18, RASI
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6202a was selected from the C-term region of human MMP19 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP19
Synonyms MMP18, RASI
Function Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease). May also play a role in neovascularization or angiogenesis. Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls. Not detected in brain and peripheral blood leukocytes. Also expressed in the synovial fluid of normal and rheumatoid patients
Research Areas
Citations (0)

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP19 has not been determined. This gene was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19).


Sadowski, T., et al., Mol. Biol. Cell 14(11):4569-4580 (2003).Impola, U., et al., Int. J. Cancer 103(6):709-716 (2003).Mauch, S., et al., J. Immunol. 168(3):1244-1251 (2002).Stracke, J.O., et al., J. Biol. Chem. 275(20):14809-14816 (2000).Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).

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$ 80.00
Cat# BP6202a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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