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MMP20 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O60882
Other Accession NP_004762
Clone Names 2090503
Peptide ID 2090503
Additional Information
Gene ID 9313
Other Names Matrix metalloproteinase-20, MMP-20, 3424-, Enamel metalloproteinase, Enamelysin, MMP20
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6203a was selected from the Center region of human MMP20 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP20
Function Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation.
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Expressed specifically in the enamel organ.
Research Areas
Citations (0)

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Background

MMP20 degrades amelogenin, the major protein component of the enamel matrix, as well as two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). MMP20 may play a central role in tooth enamel formation.

References

Llano, E., et al., Biochemistry 36(49):15101-15108 (1997).Stracke, J.O., et al., FEBS Lett. 478 (1-2), 52-56 (2000).

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$ 80.00
Cat# BP6203a
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