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MMP3 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P08254
Other Accession NP_002413
Clone Names 2090301
Peptide ID 2090301
Additional Information
Gene ID 4314
Other Names Stromelysin-1, SL-1, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6211a was selected from the Center region of human MMP3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP3
Synonyms STMY1
Function Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.


Sage, E.H., et al., J. Biol. Chem. 278(39):37849-37857 (2003).Matsuyama, A., et al., Circulation 108(12):1469-1473 (2003).Mercapide, J., et al., Int. J. Cancer 106(5):676-682 (2003).Bodemer, C., et al., J. Invest. Dermatol. 121(2):273-279 (2003).Kang, M.K., et al., Exp. Cell Res. 287(2):272-281 (2003).

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$ 80.00
Cat# BP6211a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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