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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NRG4 Antibody Blocking Peptide   

NRG4 Antibody Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8WWG1
Additional Information
Gene ID 145957
Other Names Pro-neuregulin-4, membrane-bound isoform, Pro-NRG4, Neuregulin-4, NRG-4, NRG4
Target/Specificity The synthetic peptide sequences used to generate the antibody AP6225a was selected from the center and C-terminal region of human NRG4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRG4
Function Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors (By similarity).
Cellular Location Pro-neuregulin-4, membrane-bound isoform: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active.
Research Areas
Citations (0)

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The nuclear protein p100 is a proliferation-associated protein whose expression is restricted to cell cycle phases S, G2, and M. Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. The full-length cDNA encodes a 747-amino acid protein with a putative ATP/GTP-binding site motif. RT-PCR analysis demonstrated strong expression of in lung carcinoma cell lines but not in normal lung tissues. Expression was also found in adult placenta, skeletal muscle, thymus, testis, and small intestine and in fetal brain, liver, and kidney. P100 is also correlated to cancer prognosis.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).

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$ 80.00
Cat# BP6225a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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