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EDA Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q92838
Clone Names 71009119
Peptide ID 71009119
Additional Information
Gene ID 1896
Other Names Ectodysplasin-A, Ectodermal dysplasia protein, EDA protein, Ectodysplasin-A, membrane form, Ectodysplasin-A, secreted form, EDA, ED1, EDA2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6281a was selected from the N-term region of human EDA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDA
Synonyms ED1, EDA2
Function Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.
Cellular Location Cell membrane; Single-pass type II membrane protein
Tissue Location Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord. {ECO:0000269|Ref.6}
Research Areas
Citations (0)

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EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. This protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in the gene for EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia.


Tariq,M., Eur J Dermatol 17 (3), 209-212 (2007)Tarpey,P., Am. J. Med. Genet. A 143 (4), 390-394 (2007)

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$ 80.00
Cat# BP6281a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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