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GRB2 Antibody (Y209) Blocking PeptideSynthetic peptide
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| BP6283a | 0.1 mg 400 ul | In Stock | $ 45.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
GRB2 Antibody (Y209) Blocking Peptide - Product info | |
| Primary Accession | P62993 |
| Clone Names | 109069 |
| Calculated MW | 25206 Da |
GRB2 Antibody (Y209) Blocking Peptide - Additional info | |
| Gene ID 2885 | |
| Target/Specificity The synthetic peptide sequence used to generate the antibody AP6283a was selected from the Y209 region of human GRB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. | |
| Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. | |
| Precautions This product is for research use only. Not for use in diagnostic or therapeutic procedures. | |
GRB2 Antibody (Y209) Blocking Peptide - Protein Information | |
| Name GRB2 | |
| Synonyms ASH | |
| Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | |
| Cellular Location Nucleus. Cytoplasm. Endosome. Golgi apparatus (By similarity) | |
GRB2 Antibody (Y209) Blocking Peptide - Related products
AP6283b: GRB2 Antibody (N-term)
AP6283c: GRB2 Antibody (Center)
LY11018a: GRB2 Over-expression Lysate
BP6283a: GRB2 Antibody (Y209) Blocking Peptide
BP6283b: GRB2 Antibody (N-term) Blocking Peptide
BP6283c: GRB2 Antibody (Center) Blocking Peptide
AJ1331a: GRB2 Antibody (C-term)
GRB2 Antibody (Y209) Blocking Peptide - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.
REFERENCES
Kondo,A., J. Biol. Chem. 283 (3), 1428-1436 (2008)Morimatsu,M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007)Martinez,N., Cell. Signal. 19 (11), 2277-2285 (2007)
