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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GRB2 Antibody (Y209) Blocking Peptide   

GRB2 Antibody (Y209) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P62993
Clone Names 109069
Peptide ID 109069
Additional Information
Gene ID 2885
Other Names Growth factor receptor-bound protein 2, Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2, GRB2, ASH
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6283a was selected from the Y209 region of human GRB2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRB2
Synonyms ASH
Function Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
Cellular Location Nucleus. Cytoplasm. Endosome. Golgi apparatus
Research Areas
Citations (0)

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GRB2 binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway.


Kondo,A., J. Biol. Chem. 283 (3), 1428-1436 (2008)Morimatsu,M., Proc. Natl. Acad. Sci. U.S.A. 104 (46), 18013-18018 (2007)Martinez,N., Cell. Signal. 19 (11), 2277-2285 (2007)

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$ 80.00
Cat# BP6283a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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