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CD14 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P08571
Clone Names 71017125
Peptide ID 71017125
Additional Information
Gene ID 929
Other Names Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, Monocyte differentiation antigen CD14, urinary form, Monocyte differentiation antigen CD14, membrane-bound form, CD14
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6294b was selected from the C-term region of human CD14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD14
Function In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages
Research Areas
Citations (0)

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CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells.


Donati,M., J. Periodontol. 79 (3), 517-524 (2008)Yuan,F.F., Immunol. Cell Biol. 86 (3), 268-270 (2008)Setoguchi,M., Biochim. Biophys. Acta 1008 (2), 213-222 (1989)Goyert,S.M., Science 239 (4839), 497-500 (1988)

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$ 80.00
Cat# BP6294b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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