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DSCR1L1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q14206
Clone Names 2100203
Additional Information
Gene ID 10231
Other Names Calcipressin-2, Down syndrome candidate region 1-like 1, Myocyte-enriched calcineurin-interacting protein 2, MCIP2, Regulator of calcineurin 2, Thyroid hormone-responsive protein ZAKI-4, RCAN2, DSCR1L1, ZAKI4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6316b was selected from the N-term region of human DSCR1L1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RCAN2
Synonyms DSCR1L1, ZAKI4
Function Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
Tissue Location Expressed in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas
Research Areas
Citations (0)
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Background

DSCR1L1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. This protein may play a role during central nervous system development. Expression is detected in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. Expression of both transcripts is upregulated by physiologic concentrations of the thyroid hormone triiodothyroxine.

References

Rothermel, B., et al., J. Biol. Chem. 275(12):8719-8725 (2000).Fuentes, J.J., et al., Hum. Mol. Genet. 9(11):1681-1690 (2000).Strippoli, P., et al., Genomics 64(3):252-263 (2000).Miyazaki, T., et al., J. Biol. Chem. 271(24):14567-14571 (1996).Cao, X., et al., Biochem. J. 367 (PT 2), 459-466 (2002) (): ().

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$ 277.78
Cat# BP6316b
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