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DSCR3 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O14972
Clone Names 2093001
Additional Information
Gene ID 10311
Other Names Down syndrome critical region protein 3, Down syndrome critical region protein A, DSCR3, DCRA, DSCRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6319b was selected from the C-term region of human DSCR3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSCR3
Synonyms DCRA, DSCRA
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Background

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined.

References

Dahmane, N., et al., Genomics 48(1):12-23 (1998).Nakamura, A., et al., J. Biochem. 122(4):872-877 (1997).

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$ 80.00
Cat# BP6319b
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