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DSCR4 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P56555
Clone Names 2093003
Additional Information
Other Names Down syndrome critical region protein 4, Down syndrome critical region protein B, DSCR4, DCRB, DSCRB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6319c was selected from the N-term region of human DSCR4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSCR4
Synonyms DCRB, DSCRB
Tissue Location Mainly expressed in placenta. EMBL; AB000099; BAA25877.1; -; mRNA EMBL; BC069729; AAH69729.1; -; mRNA EMBL; BC096162; AAH96162.1; -; mRNA EMBL; BC096163; AAH96163.1; -; mRNA EMBL; BC096164; AAH96164.1; -; mRNA CCDS; CCDS33554.1; - RefSeq; NP_005858.1; NM_005867.3 UniGene; Hs.23251; - UniGene; Hs.744972; - ProteinModelPortal; P56555; - BioGrid; 115570; 2 IntAct; P56555; 1 STRING; 9606.ENSP00000381921; - iPTMnet; P56555; - PhosphoSitePlus; P56555; - BioMuta; DSCR4; - PaxDb; P56555; - PRIDE; P56555; - DNASU; 10281; - Ensembl; ENST00000328264; ENSP00000328676; ENSG00000184029 GeneID; 10281; - KEGG; hsa:10281; - UCSC; uc002ywp.3; human CTD; 10281; - DisGeNET; 10281; - GeneCards; DSCR4; - HGNC; HGNC:3045; DSCR4 HPA; HPA018460; - MIM; 604829; gene neXtProt; NX_P56555; - OpenTargets; ENSG00000184029; - PharmGKB; PA27497; - eggNOG; ENOG410KC5P; Eukaryota eggNOG; ENOG4110T2K; LUCA GeneTree; ENSGT00390000011636; - HOGENOM; HOG000112278; - InParanoid; P56555; - BioCyc; ZFISH:G66-32646-MONOMER; - GenomeRNAi; 10281; - PRO; PR:P56555; - Proteomes; UP000005640; Chromosome 21 Bgee; ENSG00000184029; - CleanEx; HS_DSCR4; - ExpressionAtlas; P56555; baseline and differential Genevisible; P56555; HS 2: Evidence at transcript level; Complete proteome; Reference proteome CHAIN 1 118 Down syndrome critical region protein 4 /FTId=PRO_0000080019 SEQUENCE 118 AA; 12955 MW; 97CE8D8A85F447BF CRC64; MSLIILTRDD EPRIFTPDSD AASPALHSTS PLPDPASASP LHREEKILPK VCNIVSCLSF SLPASPTDSG LASPTIITRE GQQFWAKCLI WKYQLYLHGL HKKSDGRRDK QISASPST
Research Areas
Citations (0)

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Background

The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and mental retardation. The gene for this protein is found in this region and multiple transcripts may exist. It is mainly expressed in the placenta.

References

Dahmane, N., et al., Genomics 48(1):12-23 (1998).Nakamura, A., et al., DNA Res. 4(5):321-324 (1997).

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$ 80.00
Cat# BP6319c
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