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DSCR6 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P57055
Additional Information
Gene ID 53820
Other Names Protein ripply3, Down syndrome critical region protein 6, RIPPLY3, DSCR6
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6322d was selected from the N-term region of human DSCR6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DSCR6
Function Acts as a transcriptional corepressor. Negative regulator of the transcriptional activity of TBX1. Plays a role in the development of the pharyngeal apparatus and derivatives (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed at a low level in fetal kidney and fetal brain.
Research Areas
Citations (0)

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The DSCR6 gene is located in the Down syndrome critical region (DSCR) on chromosome 21q22.2, in the overlapping region of partial trisomy 21 patients. While the DSCR5 gene is expressed in a variety of human tissues, the DSCR6 gene is expressed only in limited tissues at low level. DSCR6 is a candidate for the pathogenesis of Down syndrome.


Shibuya, K., et al., Biochem. Biophys. Res. Commun. 271(3):693-698 (2000).

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$ 80.00
Cat# BP6322d
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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