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MYO5A Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y4I1
Clone Names 4111107
Additional Information
Gene ID 4644
Other Names Unconventional myosin-Va, Dilute myosin heavy chain, non-muscle, Myosin heavy chain 12, Myosin-12, Myoxin, MYO5A, MYH12
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6352b was selected from the Center region of human Myo5A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYO5A
Synonyms MYH12
Function Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.
Tissue Location Detected in melanocytes.
Research Areas
Citations (0)

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Background

Myo5A is a processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. This protein is involved in melanosome transport, and may also be required for some polarization process involved in dendrite formation.

References

Passeron, T., et al., FASEB J. 18(9):989-991 (2004).Menasche, G., et al., J. Clin. Invest. 112(3):450-456 (2003).Westbroek, W., et al., J. Invest. Dermatol. 120(3):465-475 (2003).Fukuda, M., et al., J. Biol. Chem. 277(14):12432-12436 (2002).Ohashi, S., et al., J. Biol. Chem. 277(40):37804-37810 (2002).

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$ 80.00
Cat# BP6352b
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