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GPR81 Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9BXC0
Other Accession NP_115943
Additional Information
Gene ID 27198
Other Names Hydroxycarboxylic acid receptor 1, G-protein coupled receptor 104, G-protein coupled receptor 81, HCAR1, GPR104, GPR81, HCA1
Target/Specificity The synthetic peptide sequence is selected from aa 296~322 of HUMAN HCAR1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HCAR1
Synonyms GPR104, GPR81, HCA1
Function Acts as a receptor for L-lactate and mediates its anti- lipolytic effect through a G(i)-protein-mediated pathway.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.
Research Areas
Citations (0)
citation

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Background

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. Northern analyses revealed GPR81 expression in the pituitary.

References

Mao, M., et al., Genomics 83(6):989-999 (2004).
Lee, D.K., et al., Gene 275(1):83-91 (2001).

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$ 277.78
Cat# BP6361b
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