|Other Names||Hepatoma-derived growth factor, HDGF, High mobility group protein 1-like 2, HMG-1L2, HDGF, HMG1L2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6375a was selected from the N-term region of human HDGF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.|
|Cellular Location||Cytoplasm. Nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
HDGF is a member of the hepatoma-derived growth factor family. This protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation.
Thakar,K., FEBS J. 275 (7), 1411-1426 (2008)Chang,K.C.,Int. J. Cancer 121 (5), 1059-1065 (2007)Yamamoto,S., Ann. Surg. Oncol. 14 (7), 2141-2149 (2007)Uyama,H., Clin. Cancer Res. 12 (20 PT 1), 6043-6048 (2006)
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