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PLD1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q13393
Clone Names 71211150
Peptide ID 71211150
Additional Information
Gene ID 5337
Other Names Phospholipase D1, PLD 1, hPLD1, Choline phosphatase 1, Phosphatidylcholine-hydrolyzing phospholipase D1, PLD1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6377a was selected from the N-term region of human PLD1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLD1
Function Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
Cellular Location Cytoplasm, perinuclear region. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Late endosome membrane; Lipid- anchor; Cytoplasmic side
Tissue Location Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
Research Areas
Citations (0)

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Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995 [PubMed 8530346]).[supplied by OMIM]


Sun,Y., Proc. Natl. Acad. Sci. U.S.A. 105 (24), 8286-8291 (2008)Sethu,S., J. Immunol. 180 (9), 6027-6034 (2008)Nagasaki,A., Cell Struct. Funct. 33 (1), 27-33 (2008)

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$ 80.00
Cat# BP6377a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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