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Paxillin (PXN) Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P49023
Clone Names 70411240
Peptide ID 70411240
Additional Information
Gene ID 5829
Other Names Paxillin, PXN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6408c was selected from the Center region of human PXN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PXN
Function Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Cellular Location Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Note=Colocalizes with integrins at the cell periphery.
Research Areas
Citations (0)

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PXN is a cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. PXN contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).


Doan,A.T.,Exp. Cell Res. 313 (12), 2667-2679 (2007)Birukova,A.A.,Am. J. Physiol. Lung Cell Mol. Physiol. 293 (1), L199-L211 (2007)Gehmlich,K.,J. Mol. Biol. 369 (3), 665-682 (2007)Rathore,V.B.,Biochem. J. 403 (2), 275-281 (2007)

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$ 80.00
Cat# BP6408c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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