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EDNRA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P25101
Clone Names 80513107
Peptide ID 80513107
Additional Information
Gene ID 1909
Other Names Endothelin-1 receptor, Endothelin A receptor, ET-A, ETA-R, hET-AR, EDNRA, ETA, ETRA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6507c was selected from the Center region of human EDNRA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ETA, ETRA
Function Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and liver but no expression in umbilical vein endothelial cells. Within the placenta, isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in the villi and stem villi vessels.
Research Areas
Citations (0)

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EDNRA is a receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.


Cardillo,C., Arthritis Rheum. 60 (6), 1840-1844 (2009)Hayzer,D.J., Am. J. Med. Sci. 304 (4), 231-238 (1992)

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$ 80.00
Cat# BP6507c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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