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CAV3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P56539
Clone Names 80808053
Peptide ID 80808053
Additional Information
Gene ID 859
Other Names Caveolin-3, M-caveolin, CAV3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6516a was selected from the N-term region of human CAV3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAV3
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.
Cellular Location Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity)
Tissue Location Expressed predominantly in muscle.
Research Areas
Citations (0)

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CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in its gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD).


Garg,V., Biochem. Biophys. Res. Commun. 385 (3), 472-477 (2009)Cai,C., . Biol. Chem. 284 (23), 15894-15902 (2009)

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$ 80.00
Cat# BP6516a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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