|Other Names||Regulatory solute carrier protein family 1 member 1, Transporter regulator RS1, hRS1, RSC1A1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6534a was selected from the N-term region of human RSC1A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Mediates transcriptional and post-transcriptional regulation of SLC5A1. Inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1. Also involved in transcriptional regulation of SLC22A2. Exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network.|
|Cellular Location||Cell membrane. Nucleus. Golgi apparatus, trans- Golgi network. Note=Localizes at the inner side of the plasma membrane|
|Tissue Location||Expressed in small intestine, kidney and brain.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
RSC1A1 mediates transcriptional and post-transcriptional regulation of SLC5A1. The protein inhibits a dynamin and PKC-dependent exocytotic pathway of SLC5A1 and is also involved in transcriptional regulation of SLC22A2. It exhibits glucose-dependent, short-term inhibition of SLC5A1 and SLC22A2 by inhibiting the release of vesicles from the trans-Golgi network.
Vernaleken,A., J. Biol. Chem. 282 (39), 28501-28513 (2007)Kroiss,M., Am. J. Physiol. Renal Physiol. 291 (6), F1201-F1212 (2006)Veyhl,M., Am. J. Physiol. Renal Physiol. 291 (6), F1213-F1223 (2006)
If you have any additional inquiries please email technical services at email@example.com.