|Other Names||Mitochondrial import inner membrane translocase subunit TIM14, DnaJ homolog subfamily C member 19, DNAJC19, TIM14, TIMM14|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6542b was selected from the C-term region of human DNAJC19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
DNAJC19 is a probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. The protein may act as a co-chaperone that stimulate the ATP-dependent activity.
Sparkes,R., Cardiol Young 17 (2), 215-217 (2007)Davey,K.M., J. Med. Genet. 43 (5), 385-393 (2006)Mokranjac,D., EMBO J. 22 (19), 4945-4956 (2003)
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