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ERG Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P11308 |
|---|---|
| Clone Names | 80821014 |
| Gene ID | 2078 |
|---|---|
| Other Names | Transcriptional regulator ERG, Transforming protein ERG, ERG |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6552b was selected from the C-term region of human ERG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ERG |
|---|---|
| Function | Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237, ECO:0000269|PubMed:17289661}. Cytoplasm Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs |
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Provided below are standard protocols that you may find useful for product applications.
Background
ERG is a transcriptional regulator. The protein may participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent modification of local chromatin structure.
References
Rostad,K., APMIS 117 (8), 575-582 (2009)Yuan,L., Circ. Res. 104 (9), 1049-1057 (2009)Attard,G., Cancer Res. 69 (7), 2912-2918 (2009)
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