|Other Names||Carboxypeptidase A1, CPA1, CPA|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6560a was selected from the N-term region of human CPA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.|
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Provided below are standard protocols that you may find useful for product applications.
Three different forms of human pancreatic procarboxypeptidase A have been isolated. CPA1 is a monomeric pancreatic exopeptidase involved in zymogen inhibition.
Pallares,I., Acta Crystallogr. D Biol. Crystallogr. D64 (PT 7), 784-791 (2008)Bonora,E., Mol. Psychiatry 7 (3), 289-301 (2002)
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