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CPA1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P15085 |
|---|---|
| Clone Names | 80410121 |
| Gene ID | 1357 |
|---|---|
| Other Names | Carboxypeptidase A1, CPA1, CPA |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6560a was selected from the N-term region of human CPA1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CPA1 (HGNC:2296) |
|---|---|
| Synonyms | CPA |
| Function | Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro (PubMed:8806703). Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond (By similarity). |
| Cellular Location | Secreted. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Three different forms of human pancreatic procarboxypeptidase A have been isolated. CPA1 is a monomeric pancreatic exopeptidase involved in zymogen inhibition.
References
Pallares,I., Acta Crystallogr. D Biol. Crystallogr. D64 (PT 7), 784-791 (2008)Bonora,E., Mol. Psychiatry 7 (3), 289-301 (2002)
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