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PSA Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P55786
Clone Names 80722084
Peptide ID 80722084
Additional Information
Gene ID 9520
Other Names Puromycin-sensitive aminopeptidase, PSA, Cytosol alanyl aminopeptidase, AAP-S, NPEPPS, PSA
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6563b was selected from the C-term region of human PSA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PSA
Function Aminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway for MHC class I molecules. Involved in the N-terminal trimming of cytotoxic T-cell epitope precursors. Digests the poly-Q peptides found in many cellular proteins. Digests tau from normal brain more efficiently than tau from Alzheimer disease brain.
Cellular Location Cytoplasm, cytosol. Nucleus
Tissue Location Detected in liver, epithelium of renal tubules, epithelium of small and large intestine, gastric epithelial cells, and alveoli of the lung (at protein level)
Research Areas
Citations (0)

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PSA is the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle.


Thompson,M.W., Peptides 24 (9), 1359-1365 (2003)

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$ 80.00
Cat# BP6563b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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