|Other Names||Mimecan, Osteoglycin, Osteoinductive factor, OIF, OGN, OIF, SLRR3A|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6578a was selected from the N-term region of human OGN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
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Provided below are standard protocols that you may find useful for product applications.
OGN is a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR).
Williamson,R.E., Hear. Res. 237 (1-2), 57-65 (2008)
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