|Other Names||Krueppel-like factor 6, B-cell-derived protein 1, Core promoter element-binding protein, GC-rich sites-binding factor GBF, Proto-oncogene BCD1, Suppressor of tumorigenicity 12 protein, Transcription factor Zf9, KLF6, BCD1, COPEB, CPBP, ST12|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6588a was selected from the N-term region of human COPEB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||BCD1, COPEB, CPBP, ST12|
|Function||Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development.|
|Tissue Location||Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus|
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Provided below are standard protocols that you may find useful for product applications.
COPEB is a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor.
Sangodkar,J., Eur. J. Cancer 45 (4), 666-676 (2009)DiFeo,A., Drug Resist. Updat. 12 (1-2), 1-7 (2009)
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