|Other Names||Tumor necrosis factor alpha-induced protein 2, TNF alpha-induced protein 2, Primary response gene B94 protein, TNFAIP2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6593c was selected from the Center region of human TNFAIP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May play a role as a mediator of inflammation and angiogenesis.|
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Provided below are standard protocols that you may find useful for product applications.
TNFAIP2 expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that its gene may be a retinoic acid target gene in acute promyelocytic leukemia.
Rusiniak,M.E., Cancer Res. 60 (7), 1824-1829 (2000)
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