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ARF3 Antibody (Center D93) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P61204
Clone Names 80924061
Peptide ID 80924061
Additional Information
Gene ID 377
Other Names ADP-ribosylation factor 3, ARF3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6600c was selected from the Center region of human ARF3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARF3
Function GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Cellular Location Golgi apparatus. Cytoplasm, perinuclear region
Research Areas
Citations (0)

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Background

ADP-ribosylation factor 3 (ARF3) is a member of the human ARF family. These small guanine nucleotide-binding proteins stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. ARF3 include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization.

References

Li,F., FEBS Lett. 524 (1-3), 49-53 (2002)Lee,F.J., J. Biol. Chem. 267 (34), 24441-24445 (1992)

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$ 80.00
Cat# BP6600c
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