|Other Names||Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6615c was selected from the Center region of human CFHL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1,|
|Function||Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
CFHL1 might be involved in complement regulation. The protein can associate with lipoproteins and may play a role in lipid metabolism.
Grosskinsky,S., PLoS ONE 4 (3), E4858 (2009)Siegel,C., J. Biol. Chem. 283 (50), 34855-34863 (2008)
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