RALGPS1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5JS13 |
---|---|
Clone Names | 80924156 |
Gene ID | 9649 |
---|---|
Other Names | Ras-specific guanine nucleotide-releasing factor RalGPS1, Ral GEF with PH domain and SH3-binding motif 1, Ral guanine nucleotide exchange factor 2, RalGEF 2, RalA exchange factor RalGPS1, RALGPS1, KIAA0351, RALGEF2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6616c was selected from the Center region of human RALGPS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | RALGPS1 |
---|---|
Synonyms | KIAA0351, RALGEF2 |
Function | Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. |
Cellular Location | Cytoplasm. Cell membrane. Note=Associates with membranes through the PH domain |
Tissue Location | Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
RALGPS1 may be involved in cytoskeletal organization. The protein may also be involved in the stimulation of transcription in a Ras-independent fashion. It is a guanine nucleotide exchange factor for the small GTPase RALA.
References
de Bruyn,K.M., J. Biol. Chem. 275 (38), 29761-29766 (2000)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.