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SHC2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P98077
Clone Names 80924202
Peptide ID 80924202
Additional Information
Gene ID 25759
Other Names SHC-transforming protein 2, Protein Sck, SHC-transforming protein B, Src homology 2 domain-containing-transforming protein C2, SH2 domain protein C2, SHC2, SCK, SHCB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6621a was selected from the N-term region of human SHC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SHC2
Synonyms SCK, SHCB
Function Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity).
Tissue Location Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus
Research Areas
Citations (0)

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Background

SHC2 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. It is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

References

Liu,H.Y., J. Biol. Chem. 277 (29), 26046-26056 (2002)

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$ 80.00
Cat# BP6621a
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