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CTDP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9Y5B0
Clone Names 81028005
Peptide ID 81028005
Additional Information
Gene ID 9150
Other Names RNA polymerase II subunit A C-terminal domain phosphatase, TFIIF-associating CTD phosphatase, CTDP1, FCP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6634a was selected from the N-term region of human CTDP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTDP1
Synonyms FCP1
Function Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation.
Cellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Found at centrosomes in prometaphase, at spindle and spindle poles in metaphase and at spindle midzone and midbody in anaphase and telophase-G1 respectively
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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CTDP1 is a protein which interacts with the carboxy-terminus of transcription initiation factor TFIIF, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. The protein may also represent a component of an RNA polymerase II holoenzyme complex.


Hirose,Y., Biochem. Biophys. Res. Commun. 369 (2), 449-455 (2008)Abbott,K.L., Biochemistry 44 (8), 2716-2731 (2005)

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$ 80.00
Cat# BP6634a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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