DREV Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H1A3 |
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Clone Names | 81006102 |
Gene ID | 51108 |
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Other Names | Methyltransferase-like protein 9, DORA reverse strand protein, DREV, DREV1, METTL9, DREV |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6636b was selected from the C-term region of human DREV. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | METTL9 {ECO:0000303|PubMed:33563959, ECO:0000312|HGNC:HGNC:24586} |
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Function | Protein-histidine N-methyltransferase that specifically catalyzes 1-methylhistidine (pros-methylhistidine) methylation of target proteins (PubMed:33563959, PubMed:34562450). Mediates methylation of proteins with a His-x-His (HxH) motif (where 'x' is preferably a small amino acid) (PubMed:33563959). Catalyzes methylation of target proteins such as S100A9, NDUFB3, SLC39A5, SLC39A7, ARMC6 and DNAJB12; 1-methylhistidine modification may affect the binding of zinc and other metals to its target proteins (PubMed:33563959, PubMed:34562450). Constitutes the main methyltransferase for the 1- methylhistidine modification in cell (PubMed:33563959). |
Cellular Location | Endoplasmic reticulum Mitochondrion. Note=Colocalizes with membranous compartments such as the endoplasmic reticulum and mitochondria. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DREV belongs to the DREV family.
References
Shu,K.X., Colloids Surf B Biointerfaces 52 (1), 22-30 (2006)Tsang,H.T., Genomics 88 (3), 333-346 (2006)
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