|Other Names||ETS-related transcription factor Elf-1, E74-like factor 1, ELF1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6639a was selected from the N-term region of human ELF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.|
|Tissue Location||In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis.|
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Provided below are standard protocols that you may find useful for product applications.
ELF1 is an E26 transformation-specific related transcription factor. The protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes.
Juang,Y.T., J. Immunol. 181 (5), 3658-3664 (2008)Takahashi,K., J. Biol. Chem. 283 (22), 15134-15141 (2008)
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