Hb3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P78385 |
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Clone Names | 80808045 |
Gene ID | 3889 |
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Other Names | Keratin, type II cuticular Hb3, Hair keratin K210, Keratin-83, K83, Type II hair keratin Hb3, Type-II keratin Kb23, KRT83, KRTHB3 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP6651a was selected from the N-term region of human Hb3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KRT83 |
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Synonyms | KRTHB3 |
Tissue Location | Synthesis begins in the cortex 10-15 cell layers above the apex of the dermal papilla and ends abruptly in the middle of the cortex. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KRT83 is a member of the keratin family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
References
Schweizer,J., J. Cell Biol. 174 (2), 169-174 (2006)van Steensel,M.A., J. Med. Genet. 42 (3), E19 (2005)Langbein,L., Int. Rev. Cytol. 243, 1-78 (2005)
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