|Other Names||Hemopexin, Beta-1B-glycoprotein, HPX|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP6653c was selected from the Center region of human HPX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
HPX is a plasma glycoprotein that binds heme with high affinity. The protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress.
Ascenzi,P., IUBMB Life 59 (11), 700-708 (2007)
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