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PID/MTA2 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O94776
Clone Names 81020076
Peptide ID 81020076
Additional Information
Gene ID 9219
Other Names Metastasis-associated protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 protein, p53 target protein in deacetylase complex, MTA2, MTA1L1, PID
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6663b was selected from the C-term region of human PID/MTA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTA2
Synonyms MTA1L1, PID
Function May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624}
Tissue Location Widely expressed.
Research Areas
Citations (0)

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MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small family of different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.


Cui,Y., Mol. Endocrinol. 20 (9), 2020-2035 (2006)

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$ 80.00
Cat# BP6663b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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