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RANBP1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P43487
Peptide ID 81110022
Additional Information
Gene ID 5902
Other Names Ran-specific GTPase-activating protein, Ran-binding protein 1, RanBP1, RANBP1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.
Research Areas
Citations (0)

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Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.


Lonhienne, T.G., et al. J. Biol. Chem. 284(34):22549-22558(2009)Rensen, W.M., et al. Oncogene 28(15):1748-1758(2009)Tedeschi, A., et al. J. Cell. Sci. 120 (PT 21), 3748-3761 (2007)

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$ 80.00
Cat# BP6670b
(40 western blots)
Availability: In Stock
Bulk Size
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