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SP110 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9HB58
Clone Names 81110037
Peptide ID 81110037
Additional Information
Gene ID 3431
Other Names Sp110 nuclear body protein, Interferon-induced protein 41/75, Speckled 110 kDa, Transcriptional coactivator Sp110, SP110
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6675c was selected from the Center region of human SP110. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SP110
Function Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00185, ECO:0000255|PROSITE-ProRule:PRU00747, ECO:0000269|PubMed:10913195}. Note=Found in the nuclear body
Tissue Location Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.


Babb,C., Hum. Genet. 121 (3-4), 521-522 (2007)Izmailova,E., Nat. Med. 9 (2), 191-197 (2003)

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$ 80.00
Cat# BP6675c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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