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SRF Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P11831
Clone Names 81110044
Additional Information
Gene ID 6722
Other Names Serum response factor, SRF, SRF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP6677c was selected from the Center region of human SRF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRF
Function SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00251, ECO:0000269|PubMed:19350017}
Research Areas
Citations (0)

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SRF is a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).


Zhu,Y.T., J. Biol. Chem. 284 (21), 14485-14492 (2009)Raimundo,N., Oncogene 28 (9), 1261-1273 (2009)

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$ 80.00
Cat# BP6677c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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